Annette
Hi, I too suffer from degenerative bone disease. I take ultram, 50mg, 2 four times aday, and this is the only one that I have taken, that has taken the edge off of the pain. I have tried over a dozen or more over the last ten years, and I have been on this one for 3 years, and I thank god everyday, for the making of this pain medication. It has been a god sent. I hope that you too can find something that will help you with your pain.I know where you are, I am there myself. God bless you.